what does somatic recombination have to do with multiple myeloma?

Answers:
Mutation in the light chain protien that presents itself in MMtough question; I would check medical database for more or send email to the IMF so they could have science advisor answer.www.myeloma.orgJewells
30 months and still here

---

antibody variability.

---

The same thing that Bill had to do with Monica. :)

---

It shouldn't have anything to do with multiple myeloma. Multiple myeloma starts as any other cancer starts, with a mutation of a gene. In this case, it is a mutation that occurs in plasma cells. Now, somatic recombination is involved with the selection of antibodies, which plasma cells secrete. But the malignancy does not relate to the recombination that produces the antibodies. It has to do with a mutation in the reproductive genetics of the cell, and not the cell's products.

---